By D. van Elswijk, T. Schenk, U. R. Tjaden (auth.), Prof. Dr. Bertold Hock (eds.)
Bioresponse-linked instrumental research combines biomolecular attractiveness, beginning a organic impression within the organism, and chemical research. even if this expertise is just at its starting, the ability of this method is clear. It offers either, details on results with appreciate to the utilized objective buildings in addition to the chemical constitution and focus of lively components found in a pattern. during this ebook, examples starting from endocrine disruptors to neurotoxic ingredients are used to demonstrate the principle.
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G. in the ng to pg range). For its part, the use of instrumental analysis requires previous selective enrichment of the active substance from the particular matrix: A fine analytical separation precedes identification with the aid of selected reference substances followed up by quantification of the active substance. Difficulties are encountered in the selection of relevant reference substances. It is only possible to detect those substances that are actively sought by the analyst. The analysis of individual substances does not detect unknown substances or metabolites, having adverse biological or toxicological effects, in an environmental sample.
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